Cabergoline suppress lactation

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Cabergoline suppress lactation

Posted Mar 02, 2016 by Admin

PMID :. Bracco PL, Armentano G, Pellegrini A et al. Cabergoline in the inhibition of lactogenesis and suppression of lactopoiesis. Minerva Ginecol. 1997;. PMID :. Pavlista D, Calda P, Zivny J. Serum prolactin was suppressed in both groups, but rebound was more common with bromocriptine on days 15 and 21. Adverse effects were numerically, but not statistically less frequent in cabergoline patients, with the most frequent being dizziness, headache, nausea and epigastric pain.7 Cabergoline was evaluated.

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Cabergoline was at least as effective as bromocriptine, with complete success in 78 of cabergoline patients and 69 of bromocriptine patients. The rate of rebound lactation was much higher in bromocriptine patients (24) than in cabergoline patients (5).

Cabergoline's use in other conditions has caused side effects similar to other dopamine agonists, such as bromocriptine. Whether rare cases of severe adverse effects occur with cabergoline as with bromocriptine cannot be determined because of the small number of postpartum patients treated in clinical trials.

Cabergoline dosing schedule

Lactation was completely inhibited in 92 of women; 8 women required a second doses of 1 mg to inhibit lactation. Twenty-six percent of women had side effects such as dizziness, headache, nausea and abdominal pain.

1991;. PMID :. European Multicentre Study Group for Cabergoline in Lactation Inhibition. Single dose cabergoline versus bromocriptine in inhibition of puerperal lactation: randomised, double blind, multicentre study. Br Med J. 1991;.

Arrest of lactation after 2nd trimester abortion with a single dose of cabergoline in comparison with 10-day administration of teguride. Ceska Gynekol. 2003;. PMID :. Bravo-Topete EG, Mendoza-Hernandez F et al.

Only composite results were given for the entire group of 100 women. Mean serum prolactin dropped from 181.4 mcg/L (range 153 to 213 mcg/L) on the first day to 12.5 mcg/L (range 0.9 to 37 mcg/L) on day 4, and 18.2 mcg/L (range 2 to.

A treatment scheme has been reported for mothers with hypergalactia that uses low doses of cabergoline to decrease milk supply.12 Drug Levels Maternal Levels. Relevant published information was not found as of the revision date.

Prescrire Int. 2015;. 3. Melis GB, Gambacciani M et al. Dose-related prolactin inhibitory effect of the new long-acting dopamine receptor agonist cabergoline in normal cycling, puerperal, and hyperprolactinemic women. J Clin Endocrinol Metab.