In contrast to the study of Colao et al. where patients were selected for withdrawal on the basis of multiple parameters and were subjected to a step-wise withdrawal protocol, Pituitary Society Guidelines are more generally worded as to be practical in routine clinical care.Main Outcome.
Five of the six recently published studies in prolactinoma patients evaluated the relation between the use of cabergoline and morphological changes of the valves, and one study found significantly more frequent thickening and calcifications of cardiac valves in patients treated with cabergoline compared with controls.
Cabergoline is a selective D2 agonist whereas apomorphine is a non-specific D1/D2 agonist. With its highly specific D2 receptor agonism and its favorable adverse effect profile, cabergoline may turn out to be particularly suitable for this indication.19 In another study, the global response to the.
A potential shortcoming of Cabergoline is its effect on the heart valve in people who take high doses of the drug. The Committee on Safety of Medicines in the United Kinkdom recommends 6-12 monthly echo of the heart.
There may be other side effects as well. You need to inform your doctor about the side effects if they persist for long. Drug Interactions: There are several medicines which may interact with the working of the medicine and thereby may cause some serious harm.Buy.
Rare (affecting less than 1 in 1000 but more than 1 in 10,000 people Pain in the upper abdomen. Very rare (affecting less than 1 in 10,000) and not known: Angina, pulmonary fibrosis shells, inflammation of the lung lining, chest pain, visual disturbances, tremors of.Pulmonary fibrosis nosebleeds, hypersensitivity reaction, transient loss of vision in one half of the visual field, fainting, feelings of numbness, increased libido, spasm of blood vessels of the fingers, loss of consciousness, edema, peripheral edema, rash, hair loss, muscle cramps in the legs, lower hemoglobin. If you wish to become pregnant should stop taking DOSTINEX one month before the start of attempts to become pregnant. During treatment, it may need to regularly take pregnancy tests, as well as to explore vaginal discharge.
Important information about some of the ingredients of DOSTINEX. DOSTINEX contains lactose. If your doctor has told you that you have an intolerance to some sugars, contact him before taking this medicine.If the first being treated with this product, you can monitor blood pressure. There are reports of pathological undue risks, acute mental disorder, a tendency to self-deception, respiratory disorders, respiratory failure.
In this case, the observed side effects should lessen or disappear completely. 5. How to store DOSTINEX Do not store above 25 C. Keep out of reach of children. DOSTINEX tablets should be stored in the bottle.If fibrotic reactions occur, treatment should be stopped. If you develop signs and / or symptoms of respiratory disease or heart damage, your doctor may decide to do some research and eventually stop treatment.
Before you start using cabergoline should not exclude the possibility that you are pregnant. It should also take care to protect yourself from getting pregnant for at least a month after you have stopped treatment with cabergoline.By lowering the amount of his DOSTINEX can restore the ability to become pregnant. DOSTINEX is intended to prevent or stop lactation after childbirth or its withdrawal once you suck. DOSTINEX is applied and in diseases caused by an increased level of prolactin - such.
Do not take a double dose to make up the missed dose. If you have any further questions on the use of this product, ask your doctor or pharmacist. 4. Possible side effects Like all medicines, DOSTINEX can cause side effects, although not everybody gets.If any of these effects bother you, tell your doctor. He may consider temporarily lowering the dosage in case of severe adverse reactions, and subsequently gradually increases with 1/2 tablet (0,25mg) weekly for 2 weeks.
Medication Name.If you take more than the amount DOSTINEX. In this case, contact your doctor immediately. If you forget to take DOSTINEX If you forget to take your 1 or 1/2 tablet in due time, take it as soon as you remember.
There are insufficient data regarding the influence of alcohol during treatment is therefore not recommended for use alcohol. Could occur somnolence and episodes of sudden sleep onset. Pregnancy, lactation and fertility Ask your doctor or pharmacist before taking any medicine.In case you are treated with DOSTINEX for an extended period of time, your doctor will check before starting treatment whether your heart, lungs and kidneys are in good condition. He / she will also have an echocardiogram (an ultrasound test of the heart) before.
The usual dose for preventing lactation: 1 mg (2 tablets) at the first day after birth. The usual dose for stopping lactation: 1/2 tablet every 12 hours for 2 days. The usual dose for reducing the secretion of prolactin in other conditions with 0,5 mg.Early symptoms may be one or more of the following: difficulty breathing, shortness of breath, chest pain or back pain and swollen legs. If you experience any of these symptoms, you should immediately inform your doctor; Indigestion, gastritis, fatigue, tiredness; In the treatment of conditions.
Common side effects (affecting less than 1 in 10 but more than 1 in 100 people Drowsiness, depression, blood pressure lowering, a sharp decrease in blood pressure when standing up, asymptomatic decrease in blood pressure, constipation, pain in the chest; When braking, suppression of lactation.During taking your medicine can watch any of the following side effects: Very common side effects (affecting more than 1 in 10 people Valvulopathy and related disorders, for example. inflammation (pericarditis) or effusion of fluid in the pericardium (pericardial effusion).
Warnings and Precautions Before take DOSTINEX tell your doctor if: you have a dysfunction of the liver or kidneys - Your doctor will do a series of tests; users of other drugs - such as medicines for nausea and vomiting (metoclopramide certain antibiotics such as.Other medicines and DOSTINEX Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. DOSTINEX with food, drinks and alcohol.