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The time to maximal effect was shorter for bromocriptine than Cabergoline (6 hours vs Cabergoline caused maternotoxicity characterized by a loss of body weight).
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Stimulating dopamine receptors reduces the production of the pituitary hormone prolactin, reduces the levels of growth hormone in people with acromegaly, and improves symptoms of Parkinson s. The FDA approved bromocriptine on June 28, 1978.Your doctor may start you on 0.375 mg and adjust your.
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1991;. PMID :. European Multicentre Study Group for Cabergoline in Lactation Inhibition. Single dose cabergoline versus bromocriptine in inhibition of puerperal lactation: randomised, double blind, multicentre study. Br Med J. 1991;. Only 1 of 8 women receiving placebo had cessation of lactation by day 14 postpartum. Serum prolactin levels collected on days 2, 3 and 4 of treatment were decreased significantly in all women who received cabergoline, but the decreases were not statistically different among the.
Cabergoline was at least as effective as bromocriptine, with complete success in 78 of cabergoline patients and 69 of bromocriptine patients. The rate of rebound lactation was much higher in bromocriptine patients (24) than in cabergoline patients (5).
Lactation was completely inhibited in 92 of women; 8 women required a second doses of 1 mg to inhibit lactation. Twenty-six percent of women had side effects such as dizziness, headache, nausea and abdominal pain.
The 1 mg dose was more effective in suppressing lactation than the 0.5 mg dose. Headache and nausea were the most common adverse effects.10 A follow-up survey was conducted on 91 women who became pregnant after treatment with cabergoline for hyperprolactinemia from pituitary adenomas.
If it is necessary, the dosage may be increased depending on the therapeutic effect and its tolerability. The increasing of the weekly dose should be done gradually (500 mg at intervals with 1 month).
PMID :. Bracco PL, Armentano G, Pellegrini A et al. Cabergoline in the inhibition of lactogenesis and suppression of lactopoiesis. Minerva Ginecol. 1997;. PMID :. Pavlista D, Calda P, Zivny J.
Serum prolactin levels collected during 13 days of treatment were decreased significantly in all women who received cabergoline, but the decreases were not statistically different among the various doses. Adverse effects included occasional dizziness and headache between days 1 and 3 after the dose.5 In.